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Not all Skinboosters are made equal – they come in different hyaluronic acid content, cross-linkages, and have different purposes. So just which skinboosters will suit your skin type and concern?

Read more as Dr. YZ Tan will explain to you how skinboosters work, how long they last and each skin booster’s unique benefits!

What are Skinboosters?

The original clinic-grade skinboosters were developed by Restylane, a Swedish-based manufacturer of dermal fillers. They were designed to ‘improve hydrobalance’ of our skin by providing long-lasting, intensified hydration from within the skin layer. Basically, they help our skin to stay moisturized, longer!

How do Skinboosters work?

Most skinboosters in the market are made of hyaluronic acid (except for Rejuran, which we will touch on more later), and help provide hydration, increase moisture levels, and increase subdermal collagen production.

Hyaluronic acid is capable of holding 1000 times its molecular weight in water, making it the gold standard ingredient for skin moisturizers and serums over skincare counters.

Studies have shown that Hyaluronic acid not only helps improves skin hydration, it also:

  • aids collagen production
  • improve skin elasticity
  • provide anti-oxidative benefits
  • accelerates wound healing
  • and reduces inflammation (that is why it is a key ingredient for Dr. Tan’s choice of moisturizer for acne-prone skin!)

Hyaluronic acid skinboosters are placed under the skin with precise injections with either an injector device or with individual manual injections after a round of topical numbing. These small deposits of skinboosters act like water reservoirs under the skin, absorbing and retaining moisture for long-term lasting hydration. This increase in hydration brightens the skin, resulting in plump, supple, and dewy skin.

Skinboosters also help increase collagen in our skin! The deposits of skinboosters increase fibroblast activity under the skin, and these fibroblast cells are responsible for collagen production. A Swedish study in 2014 reported that intradermal injection of Restylane Skinboosters resulted in increased collagen production and improved skin elasticity.

Types of Skinboosters in the market

So, what are some of the popular skinboosters available?  Let us touch on the most effective skinboosters available and approved in Singapore and how each stands out.

Restylane Vital/Vital light Skinboosters

The ‘original’ skinboosters, as these were the first skinboosters to be introduced to the market. Restylane skinboosters are partially cross-linked hyaluronic acid chains and contains up to 20mg/ml of hyaluronic acid per syringe.

Cross-linkages represents on how dense the hyaluronic acid chains are in the skinbooster. Imagine each chain having 1000 available space for water molecules to attach themselves to the hyaluronic acid. The more cross-linked the hyaluronic acid is, the less space there is for water molecules to attach themselves to. However, the more cross-linked the hyaluronic acid is, the longer the skinbooster effects last.

Teosyal Redensity I

Teosyal Redensity I, or RDI, is a Swiss-made skinbooster that is non-crossed link. Each syringe of RDI contains 15mg/ml of hyaluronic acid. The main selling point of Teosyal RDI is that it also contains 3 highly efficient and powerful antioxidants, 2 minerals, 1 vitamin and 8 amino acids. The notable antioxidants from this list is Glutathione. Glutathione is not only a powerful antioxidant, it is also the main ingredient in whitening drips (not allowed in Singapore). Therefore, Glutathione in Teosyal RDI helps makes the skin fairer while providing hydration from within. Read here on how Teoysal RD II helps with dark eye circles with Glutathione!

Juverderm Volite

Juvederm Volite is the new kid on the block in skinboosters. Juvederm Volite contains 13mg/ml of cross-linked hyaluronic acid per syringe. Although 2 syringes are required for the procedure, Juverderm Volite only requires 1 treatment compared to 3 treatments of other skinboosters, due to its unique cross-linkage and patented Vycross™ technology by Allergan (the makers of Botox and Juvederm fillers). 1 treatment of Juvederm Volite is sufficient to boost skin hydration and elasticity for up to 9 months. For those who does not fancy the downtime and injections, Juvederm Volite might just be the answer for you.

Rejuran Healer

Rejuran Healer

Rejuran Healer, one of the latest craze in aesthetic skinboosters, is not made of Hyaluronic acid – instead, it is made of PolyNucleotides (PNs), derived from salmon DNA ragments. Like Skinboosters, Rejuran is placed under the skin with precise injections and are usually placed slightly more superficially compared to most skinboosters.

Rejuran is essentially a ‘skin healer’, as its purpose is to repair cellular / DNA damange caused by both external (uv damage, pollution, etc) and internal factors (aging, scarring).

The polynucleotides in Rejuran Healer work by biologically stimulating the activity of fibroblasts in the skin. Fibroblast activity due to Rejuran is more intense compared to skinboosters as these DNA fragments directly trigger skin cells to repair themselves. Rejuran also works as a free radical scavenger – in other words, it reduces oxidative damage to our skin. Oxidative damage results from UV sun damage, pollution, stress, and ageing. Essentially, Rejuran’s results come from its ability to ‘turn back time’ and make our skin cells younger. The younger skin cells directly and indirectly improves skin hydration, skin tightening, brighter and younger looking skin, minimize pore size, and improve skin texture. Read here for more information about Rejuran Healer.

Where can skinboosters be injected?

where can you inject skinboosters on?

So which skinboosters are better for you?

Most patients at the clinic request for skinbooster brands that they already know about, and these are mostly due to online research or from friends who have done it before.

The type of skinboosters to choose will depend heavily on patients’ preferences, and also a thorough skin examination with our doctor(s).

Here is a breakdown of the different skinbooster brands and which should you consider:

types of skinboosters
table image copyright mizu aesthetic

Dr. Tan personally recommends a combination of Rejuran with Hyaluronic acid (either Restylane or Teosyal) for a skinbooster treatment, as it yields amazing results. The combined effects usually result in brighter, firmer, more hydrated, younger skin with reduced fine lines and pore size.  

As for stand-alone skinbooster treatments, Juvederm Volite is definitely one of the go-to products!

What is the preferred method of skin booster injection?

Skinbooster treatments are either done by an injector device or by manual injections.

how are skinboosters injected?

The procedure is more comfortable with the injector device but it is not suitable for Rejuran or cross-link hyaluronic acid skinboosters like Juvederm Volite as these skinboosters are more viscous and will sometimes block the injector device. The injector device also has a high chance of product leakage during injection and causes wastage.

Dr. Tan very much prefers the manual injection as it provides better effects, reduces wastage of the skinboosters, and also reduces the amount of downtime from the procedure. Manual injections are slightly more uncomfortable, but still tolerable with numbing cream.

How fast will you see results?

Results vary with individuals, but typically a non-cross linked skinboosters tend to show results after about 1-2 weeks. Rejuran, as it is more of a skin healer, takes a longer time to produce results due to the time cycle of cell rejuvenation and repair. Results typically shows after 2-3 weeks of the procedure.

How long is the downtime?

Downtime with manual injections, in the hands of a careful and experienced doctor, should only last for a maximum of 2 days with slight bumps. With an injector device, downtime tends to be 3 days or more as multiple needle punctures from the device are more forceful and can sometimes cause bruising easily.

pRelated Articles for further reading:


  1. Anna
    June 15, 2018 at 2:42 PM

    Hi! May I know how much each treatment for each type of skinboosters cost? Thanks!

    • mizu
      June 18, 2018 at 12:53 AM

      Dear Anna,

      We’ve emailed you! ; ) Do check your inbox for our response on the prices of skinboosters!

  2. June
    July 25, 2018 at 11:51 PM

    If I want to do Rejuran and Restylane Skinbooster, can I do the treatments together on the same day? If not, how many days apart before I can do the next treatment?

    Also please advise on the price of doing both treatments. Thank you.

    • mizu
      July 26, 2018 at 12:02 AM

      Hi June,

      It’s possible to mix and do both together on the same day ; )

      The recommended protocol for rejuran / restylane are the same, 3 sessions in total, each done one month apart! As for prices of Rejuran / Restylane, I’ve sent you an email on it!

  3. Elise
    August 12, 2018 at 9:47 AM

    Hello will like to know about the prices! *

    • mizu
      August 12, 2018 at 10:51 AM

      Dear Elise,

      We’ve mailed you! ; ) Hear from you soon!

  4. Wendy Teo
    August 20, 2018 at 11:57 PM

    Hi hi! Can i find out the prices of each type of treatment? and if GST is payable? Thanks!

    • mizu
      August 24, 2018 at 6:38 PM

      mailed you, Wendy! hear from you soon! ; )

  5. Fiona Chen
    September 13, 2018 at 9:50 AM

    Hi, Im keen and would like to find out more details and pricing too. Cheers! 🙂

    • mizu
      September 14, 2018 at 12:33 PM

      We’ve mailed you the prices for all skinbooster treatments available at Mizu dear. Hear from you soon! ; )

  6. Cherrie Hu
    September 23, 2018 at 8:38 AM

    Please Email me the prices

    • mizu
      September 24, 2018 at 1:06 AM

      Dear Cherrie,

      We’ve emailed you! ; )

  7. nisa
    October 27, 2018 at 3:03 PM

    Hi.. Since Rejuran Healer is known as Skin Healer. Would it be possible to to be injected on the abdomen area for stretchmarks? Please PM price as well. Thank you.

    • mizu
      October 27, 2018 at 4:39 PM

      Hi Nisa! We’ve emailed you! 😉

  8. Juni
    November 6, 2018 at 10:07 AM

    Hi, would it be possible to take different brands of skin boosters? Am interested to have Redensity because of the multivitamin and whitening benefits and Restylane for its hydrating purposes.

    • mizu
      November 6, 2018 at 8:20 PM

      Hi Juni,

      That is definitely possible! We could mix 1ml of Restylane and 1ml of Teosyal for you – so that will be a total of 2ml! ; )

  9. Lyn
    November 29, 2018 at 11:01 PM

    Hi, can you let me know the price of one session of Rejuran healer and if there is any package price? Thank you.

    • mizu
      November 30, 2018 at 1:04 PM

      Hi dear! We’ve sent you an email ; )

  10. Fiona
    January 1, 2019 at 12:58 PM

    Hi there, I’m interested in skin boosters and would like to know pricing please.


    • mizu
      January 2, 2019 at 12:36 AM

      Sent you an email, Fiona! ; )

  11. Ana
    January 1, 2019 at 10:40 PM

    Hi! May I know the price of getting these skin boosters done please? Also, how many sessions would I need to come for the treatment?

    • mizu
      January 2, 2019 at 12:36 AM

      Sent you an email, Ana! Hear from you soon!

  12. jiawen
    January 7, 2019 at 9:48 AM

    hi, am interested in this. can i have more info on the pricing? thanks!

    • mizu
      January 16, 2019 at 1:12 AM

      Hi dear! We’ve sent you an email about the prices for skinboosters! Hear from you soon ; )

  13. Jessica
    January 14, 2019 at 12:12 AM

    Hi, may I know the prices for these skinboosters please? Thanks!

    • mizu
      January 16, 2019 at 1:12 AM

      Hi dear! We’ve sent you an email about the prices for skinboosters! Hear from you soon ; )

  14. Caressa
    January 14, 2019 at 11:04 PM

    Please email me the prices. Thank you (:

    • mizu
      January 16, 2019 at 1:12 AM

      Hi dear! We’ve sent you an email about the prices for skinboosters! Hear from you soon ; )

  15. Joey
    January 15, 2019 at 9:02 AM

    Please PM me the price of skin booster treatments – RESTYLANE

    • mizu
      January 16, 2019 at 1:13 AM

      Hi Joey! We’ve sent you an email on the prices for the restylane skinboosters. Hear from you soon! ; )

  16. Christine
    March 27, 2019 at 5:01 PM

    Please PM me the prices too. Thank you

    • mizu
      March 30, 2019 at 10:36 AM

      We’ve sent you an email, Christine! ; )

  17. Chloe
    September 10, 2019 at 2:22 PM

    Can Rejuran and Redensity 1 be injected on the neck too?
    What is the best products to improve the neck skin that is getting thinner and lack of hydration ? May I know the cost too?
    Thank you.

    • mizu
      October 17, 2019 at 1:07 AM

      Hi Chloe,

      Yes they can be! We would suggest Profhilo injections specially for thinning and loose neck skin!

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