Profhilo: Still you, but younger.

Profhilo Injectable Singapore
  • Procedure Time
    45 minutes
  • Downtime
    Little to None
  • Frequency
    2x treatments, 1 ~ 2 times a year
  • Numbing Needed?
  • Discomfort Level
  • Precaution
    No drinking, smoking or exercise 24h after
The aesthetic game changer

What is Profhilo?

Profhilo - Look younger, naturally

Commonly touted as an “injectable moisturizer” on most online articles, Profhilo contains 5x more hyaluronic acid than Skinboosters and has one of the highest Hyaluronic Acid content in the market for injectables! It is also known as 逆時針 in Chinese.

An injectable treatment from IBSA, one of the world leaders in hyaluronic acid solutions, Profhilo is not a filler nor a skinbooster.

However, this soft and self-distributing injectable provides the benefits of both fillers and skinboosters at the same time for an overall skin rejuvenation effect that is subtle, yet remarkable. The change happens gradually over the course of 4 weeks, and you still look like yourself, but younger.

This is due to its unique, one-of-a-kind, manufacturing process which utilizes thermal cross-linking of both low and high molecular weight hyaluronic acid.

How does Profhilo work?

  • Provides volume to the overall area injected
  • Provides hydration (up to 5x more hyaluronic acid content than skinboosters!)
  • Invokes a bio-remodelling process of 4 types of collagen under your skin
  • Improves your skin structure and reduces skin laxity

Profhilo is able to achieve the above because it contains 100% of both low molecular and high molecular weight hyaluronic acid.

Low molecular weight hyaluronic acid works by working as a water reservoir and moisturize the skin, like a skinbooster.

High molecular weight hyaluronic acid provides a stable hyaluronic acid structure in the skin dermis to give a volumetric lift – it increases volume like a filler by increasing the production of endogenous HA (Hyaluronic Acid) and native elastin.

Profhilo stimulates elastin and collagen production to improve skin laxity, something that skinboosters and fillers cannot provide. Because it has a much smoother consistency than fillers, it spreads out evenly under the skin without forming any lumps.

The technology behind Profhilo

Prohfilo is not like a filler, nor a bio-revitaliser (like what rejuran is). It has opened up a whole new injectable category  – bio-remodeling.

The only hyaluronic acid product that does not utilize any chemical cross-linking compounds, Profhilo is thermally (using heat) bound to generate stabilized complexes of low and high molecular weight HA.

Thermal cross-linking changes the structure and behavior of Hyaluronic Acid. These thermally cross-linked Hyaluronic Acid chains are able to ‘biomodulate’ skin tissue, resulting in improvement in hydration, volume, and collagen production. Thermal cross-linking also allows both low and high molecular weight HA to be linked together, and at the same time slowly released and spread out when injected under the skin. This dual action is most ideal for re-modeling skin laxity.

It does not contain additives such BBDE or Lycodine. Its unique production process promotes homogeneous scattering and absorption in skin tissue, for safer, side-effect free results.

What & Where is Profhilo used for?

Areas of Treatment for Profhilo Injectable

Profhilo is used to treat skin laxity, improve skin quality, increase skin hydration, and increase volumetric lifting of the areas targeted. It can be used to treat skin laxity and skin quality, almost anywhere.

Common areas treated include:

  • Face
  • Neck
  • Décolletage (Chest)
  • Hands

It is most suitable for:

  • Adults experiencing skin laxity issues due to volume loss
  • Saggy, wrinkly skin
  • Those with fine lines due to dryness

Amazing as it is, Profhilo is not a replacement for fillers nor muscle-relaxing toxins. It however, gives the skin a rejuvenation and lift to further complement or boost the effect of the subsequent treatment. It will be best to speak to your doctor about what would help your issues the most.

How often do I need to do it?

The full treatment consists of two sessions, 4 weeks apart.

The first session stimulates hydration and provides a volumizing effect. The second session serves to ‘boost’ the effects, and ensure  longer lasting effects.

The effects of Profhilo is immediate, and continues to improve over 6-8 weeks. A third session can be repeated 6-12 months later depending on individuals.

Is Profhilo painful?

Profhilo is injected under the skin using very small needles.

The protocol for Profhilo on the face requires it to be injected on 5 points each side of the face. The process is made more comfortable with numbing cream applied on prior to the procedure.

Slight soreness around the injection points can sometimes be felt for the first 1-2 days.

Is there downtime?

There is minimal downtime, and most people will continue with normal activities. As with most injectable treatments, bruising and some soreness can sometimes occur.

A small bump over the injection site can be observed for a few hours after the procedure. There is no need to massage this bump as it spreads under the skin by itself.

For patients with thinner skin doing neck treatments, the bumps may stay for a longer period of time, but can be gently massaged in to reduce the downtime.

Strenuous exercise and alcohol should be avoided for 24hours after the treatment.

Are there any side effects for Profhilo?

There are no long-term side effects, as Profhilo is broken down by the body completely. It is also bio-compatible, and doesn’t cause any inflammatory reaction.

Although there are minimal side effects when injecting on the face, except for occasional bruising, it is important to make sure that you find an experienced Profhilo doctor as there are vital blood vessels to avoid when injecting in areas such as the neck.

The injection technique is important in achieving optimum results. It should not be injected too deeply into the skin, as this will not produce satisfactory results.

There are only few clinics in Singapore that have been chosen to launch Profhilo in 2019. Mizu, and our sister clinic, Aeras Medical, are two of these clinics appointed.

Profhilo vs Fillers vs Skinboosters

As compared to skinboosters, the Profhilo does more than just hydrate, requires less sessions to be done, and provides even higher  amounts of hydration!

InjectableHA ContentPain ScoreFrequencyEffects
2ml per syringe
2/102 sessions, a month apartHydration
Increases Volume
Improve Skin Quality
Reduce Skin Laxity
HA Fillers20mg/syringe
1ml per syringe
2/101 session (touchups not included)Volume replacement
Facial augmentation
1ml per syringe
4/103 sessions, a month apartHydration
Skin brightening
Rejuran Healer0mg/syringe
2ml per syringe
6-7/103 sessions, a month apartImprove Skin Quality
No hydrating effect

Profhilo is new in Singapore, but has been around for a while now in the UK and USA. Check out some of the media coverage for Profhilo from various countries:

Profhilo boosts and prolongs the effects of other hyaluronic acid treatments as well. Looking at some other things you can do alongside Profhilo? Check out our fillers and skinboosters.